8 bridges with vertical clearance data on US-378 in South Carolina. Lowest: 161.7ft.
| Clearance | Carries | Crosses | Location | Built | Map |
|---|---|---|---|---|---|
| 161.7ft | Us 378 | I-20 | 5 Mi Ne Of Lexington | 1964 | Map |
| 165.7ft | Us 378 | I-95 | 8 Mi Se Of Mayesville | 1967 | Map |
| 173.2ft | Us 378 | U.S. 52 | 1.5 Mi N Of Lake City | 2000 | Map |
| 186.4ft | Us 378 | I-26 | 4 Mi W Of Columbia | 2005 | Map |
| 222.4ft | Us 378 | S.C.L. Railroad | 1 Mi S Of Gresham | 1951 | Map |
| 234.9ft | Us 378 | S.C.L. Railroad_& L-519 | 2Mi N Of Lake City | 2004 | Map |
| 999.0ft | Us 378 | Horse Branch | 1Mi E Of Turbeville | 1938 | Map |
| 999.0ft | Us 378 Eb | Pudding Swamp | 2Mi W Of Turbeville | 1976 | Map |