23 bridges with vertical clearance data on US-21 in South Carolina. Lowest: 149.9ft.
| Clearance | Carries | Crosses | Location | Built | Map |
|---|---|---|---|---|---|
| 149.9ft | Us 21 Bus | Beaufort River | In Town Of Beaufort | 1960 | Map |
| 150.9ft | Us 21 Sb | Sc 5 | 6.4 Mi S Of Rock Hill | 1965 | Map |
| 158.5ft | Us 21 | I-20 | 5 Mi Ne Of Columbia | 1966 | Map |
| 164.0ft | Us 21 | I-26 | 8 Mi E Of Swansea | 1960 | Map |
| 167.0ft | Us 21 | Battery Creek | In Port Royal | 1994 | Map |
| 168.6ft | Us 21 | I-26 (No 2) | 6Mi S Of Cayce | 1959 | Map |
| 172.9ft | Us 21 | I-95 | 14.2 Mi Sw Walterboro | 1968 | Map |
| 181.8ft | Us 21 | Sc 5 | 6.4 Mi S Rock Hill | 1965 | Map |
| 201.8ft | Us 21 | I-77 | 2.6 Mi S Of Rock Hill | 1975 | Map |
| 211.0ft | Us 21 | S.C.9 & L & C Rr | Town Of Fort Lawn | 1961 | Map |
| 211.6ft | Us 21 | Rr Ns | 8.2 Mi S Of Rock Hill | 1954 | Map |
| 218.2ft | Us 21 | Sou- Ry.-In Ridgeway | Town Of Ridgeway | 1937 | Map |
| 220.1ft | Us 21 Sb | S-46-697 & Rr Lc | 6.9 Mi S Of Rock Hill | 1966 | Map |
| 226.0ft | Us 21 | Rr Csxt | 7 Mi S Of Columbia | 1938 | Map |
| 226.0ft | Us 21/Us 76 | Rr Csxt & Rr Ns | City Of Columbia | 1953 | Map |
| 231.0ft | Us 21_Bus | S.C.L. Railroad | In City Of Orangeburg | 1937 | Map |
| 232.6ft | Us 21 | Rr Csxt & Rr Ns | City Of Columbia | 1986 | Map |
| 250.0ft | Us 21 | Johnson Creek | 13.8 Mi Se Beaufort | 2006 | Map |
| 279.9ft | Us 21 | S.C.L. Railroad | N. City Limits -G. Falls | 1937 | Map |
| 999.0ft | Us 21 | Pen Branch | 0.25Mi S Of Branchville | 1958 | Map |
| 999.0ft | Us 21 | Early Branch | 5Mi N Of Orangeburg | 1941 | Map |
| 999.0ft | Us 21 | Saddler Swamp | 6Mi N Of Orangeburg | 1941 | Map |
| 999.0ft | Us 21 | Middle Pen Branch | In City Of Orangeburg | 1966 | Map |